Neurofibromatosis 2 (NF2) is a rare tumor suppressor syndrome that manifests with multiple schwannomas and meningiomas.There are no effective drug therapies for these benign tumors and conventional therapies have limited efficacy.Various model systems have been created and several drug targets have been implicated in NF2-driven tumorigenesis based
Abstract The emergence of SARS-CoV-2 variants that are more resistant to antibody-mediated neutralization pose a new hurdle in combating the COVID-19 pandemic.Although vaccines based on the original Wuhan sequence have been shown to be d546-430 effective at preventing COVID-19, their efficacy is likely to be decreased against more neutralization-re
In recent decades, demands for novel insecticides against mosquitoes are soaring, yet candidate chemicals with desirable properties are limited.Kathon is a broad-spectrum isothiazolinone microbicide, but other applications remain uncharacterized.First, we treated larvae of Culex quinquefasciatus and Aedes albopictus, blues cube two major mosquito v
If there was a Hall of Fame for Child and Youth Care practitioners, the first person I would nominate is Fritz Redl.I had been in the field for two years d546-430 when I first read Children Who Hate, and I was amazed at the description of youth that so accurately mirrored my own experience.Fritz and fellow author David Wineman explained CYC ideas b